Participants in the COSMA group showed +20.3% activation in the prefrontal cortex vs control group after 8 weeks. Significant improvement in working memory (p<0.01).
Significant improvement in delayed recall (RBMT-3) and sustained attention (TEA) vs care-as-usual. 92% compliance over 6 weeks.
Sustained engagement (>4 days/week) over 12 weeks. 94% user satisfaction. No significant deterioration in CDR scale during study period.
COSMA Move's in-app motor scoring correlates strongly (r=0.84, p<0.001) with Fugl-Meyer Upper Extremity Scale scores assessed by senior OT.
COSMA's assessments align with established clinical measures so results are meaningful and comparable.
In-app cognitive screener correlates with the Montreal Cognitive Assessment (MoCA) across 7 cognitive domains.
COSMA domain scores map to Mini-Mental State Examination areas for longitudinal tracking.
COSMA Move motor metrics validated against Fugl-Meyer Upper Extremity scale (r=0.84).
Addenbrooke's Cognitive Examination III domains covered: attention, memory, fluency, language, visuospatial.
University of Twente study used gold-standard RCT design with blinded assessors and matched control group.
Functional near-infrared spectroscopy confirmed brain activation increases in the prefrontal cortex during COSMA play.
We welcome collaborative research. IRB-ready data export, ethics documentation, and research pricing available.
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